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Arrival day, May 31st |
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20:00 – 21:00 |
Reception Cocktail at Porto Rio Hotel |
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Day-1, June 1st |
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08:30 – 09:00 |
Registration of participants |
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09:00 – 09:15 |
Opening: |
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Ch. Bonanos – Deputy Head of Regional Unit of Achaia, Region of Western Greece |
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G. Papatheodorou – Dean of Faculty of Natural Sciences, UP, |
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C. M. Athanassopoulos – Local organizer, UP |
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V. Cardinale – CA18122 COST Action Chair |
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09:15 – 09:25 |
EURO-CHOLANGIO-NET-overview and outputs |
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Dr. Rui Castro |
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University of Lisboa, Portugal |
| 09:25-10:00 |
Cholangiocarcinoma Status Quo: From tumor biology to novel treatments |
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Dr. Jesús Bañales |
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Biodonostia Health Research Institute, Spain |
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10:00 – 10:45 |
Development of biologically useful novel chemical entities (NCEs); |
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First proof-of-concept case study on targeting signaling pathways in |
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histological defined cholangiocarcinoma histological subtypes |
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Dr. Vincenzo Cardinale |
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Sapienza Università di Roma, Italy |
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Savino Paradiso |
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Sapienza Università di Roma, Italy |
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10:45 – 11:15 |
Coffee break |
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11:15 – 11:55 |
Generation of novel chemical entities (NCEs); |
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Natural products in drug discovery: from bench to clinic |
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Prof. Bruno Botta |
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Sapienza University of Rome |
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11:55 – 12:20 |
Diversity-oriented semi-synthetic chemical approaches in natural |
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product-inspired drug discovery |
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Dr. Attila Hunyadi |
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University of Szeged, Hungary |
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12:20 – 12:45 |
Hybrids and conjugates: Synthetic Concepts for More Effective Therapeutics |
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Dr. Constantinos Athanassopoulos |
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University of Patras, Greece |
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12:45 – 13:30 |
Innovative approaches and computational tools in drug discovery |
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Dr. Eleni Pontiki |
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Aristotelian University of Thessaloniki, Greece |
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13:30 – 15:00 |
Lunch break |
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15:00 – 15:45 |
In silico evaluation of potency and ADME(Tox) properties of drug |
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candidates; Lead optimization and drug-design using ACD/Percepta software package. |
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Dr. György T. Balogh |
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Semmelweis University, Hungary |
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| 15:45 – 16:15 |
Coffee break |
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16:15 – 17:00 |
Experimental models for the study of |
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cholangiocarcinoma: pros and cons |
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Dr. Pedro Rodrigues |
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Biodonostia Health Research Institute, Spain |
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17:00 – 17:45 |
Protection and publication of results about NCEs |
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Writing patents: general aspects, steps and costs |
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examples, claims, inventors. Phases (and costs) of patent filing |
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Prof. Fernando Cossio |
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University of the Basque Country, Spain |
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20:30 |
Gala Dinner (Dining at the Sailing Club of Patras Restaurant with a view of the spectacular sunset over Patras Bay). |
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Day-2, June 2nd |
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09:00 – 10:30 |
In silico lab: |
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Protein-ligand docking with Autodock Suite |
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Dr. Amanda R. Guimaraes |
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University of the Basque Country, Spain |
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AND |
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Dr. Constantinos Makris |
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University of Patras, Greece |
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10:30 – 11:00 |
Coffee break |
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11:00 – 11:45 |
Synthesis/web lab demonstration |
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videos illustrating key chemical reactions and chromatographic purifications |
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in Medicinal Chemistry |
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Dr. Ivàn Rivilla |
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University of the Basque Country, Spain |
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Dr. Attila Hunyadi |
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University of Szeged, Hungary |
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11:45 – 12:15 |
Synthetic Conjugates of Ursodeoxycholic Acid for the treatment of Polycystic |
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Liver Diseases and cholangiocarcinoma |
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Dr. Jesús Bañales |
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Biodonostia Health Research Institute, Spain |
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| 12:15 – 12:35 |
Design and Chemical Synthesis of Novel Chemical Entities against Cholangiocarcinoma |
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Pr. Fernando P. Cossío |
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The University of the Basque Country, Spain |
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| 12:35-13:05 |
Photochemotherapy to improve cholangiocarcinoma outcomes |
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Dr. Pilar Acedo |
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University College London, UK |
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13:05 – 13:30 |
Closing remarks |
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16:45 |
Excursion I (optional) |
| Archaelogical Museum of Patras and free time in city center Return at hotel @ 21:15 |
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June 3rd |
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09:00 |
Excursion IΙ (optional) |
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Patras’ Myceanean Cemetery site (1500 BC) and |
